CENTER for GENOME ENGINEERING

Publication Date 2025-05

Navigating ethical challenges across professions: Insights from an Ethics Lab on patient-derived organoids

Ladegaard Knox, Jeanette Bresson,Dam, Mie Seest,Green, Sara,Stange, Daniel E.,Baenke, Franziska,Bon-Kyoung Koo,Rulands, Steffen,Schmäche, Tim,Mittné, Vivian,Terlizzi, Ivan,Jahnke, Beatrix,Svendsen, Mette N.

Med, v.6, no.5

Publication Date 2025-03

Metabolic reprogramming in hepatocellular carcinoma: mechanisms and therapeutic implications

Sujin Park,Hall, Michael N.

Experimental & Molecular Medicine, v.57, no.3, pp.515 - 523

Publication Date 2025-03

Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation

England, Frances J.,Bordeu, Ignacio,Ng, Minn-E.,Bang, JaeHak,Kim, Bumsoo,Choi, Jinwook,Cardoso, Erik C.,Bon-Kyoung Koo,Simons, Benjamin D.,Lee, Joo-Hyeon

Cell Stem Cell, v.32, no.3, pp.375 - 390.e9

Publication Date 2025-02

Anticancer effect of a single-chain variable fragment against pro-matrix metalloproteinase-7 in colon cancer

Min, Shinhye,Jang, Bohee,Ji-Hye Yun,Yang, Hyeonju,Sung, Jee Young,Lim, Ga-Eun,Kim, Yong-Nyun,Lee, Weontae,Oh, Eok-Soo

Matrix Biology, v.135, pp.125 - 134

Publication Date 2025-01

RANK drives structured intestinal epithelial expansion during pregnancy

Onji, Masahiro,Sigl, Verena,Lendl, Thomas,Novatchkova, Maria,Ullate-Agote, Asier,Andersson-Rolf, Amanda,Kozieradzki, Ivona,Koglgruber, Rubina,Pai, Tsung-Pin,Lichtscheidl, Dominic,Nayak, Komal,Zilbauer, Matthias,Garcia, Natalia A. Carranza,Sievers, Laura Katharina,Falk-Paulsen, Maren,Cronin, Shane J. F.,Hagelkruys, Astrid,Sawa, Shinichiro,Osborne, Lisa C.,Rosenstiel, Philip,Pasparakis, Manolis,Ruland, Juergen,Takayanagi, Hiroshi,Clevers, Hans,Bon-Kyoung Koo,Penninger, Josef M.

Nature, v.637, no.8044, pp.156 - 166

Publication Date 2025

Genome report of Peribacillus simplex strain IMGN9 isolated from soil

Hyeonsik Yoon,Jaeyeon Lee,Yeongjun Kim,Han, Jeong A.,Ho-Seok Lee,Eun Yu Kim

Microbiology Resource Announcements, v.14, no.1

Publication Date 2024-12

Gonadal sex reversal at single-cell resolution in Znrf3-deficient mice

Kay, Raissa G G,Reeves, Richard,Siggers, Pam,Greenaway, Simon,Mallon, Ann-Marie,Wells, Sara,Bon-Kyoung Koo,Mayère, Chloé,Nef, Serge,Greenfield, Andy,Simon, Michelle M.

Development (Cambridge), v.151, no.23

Publication Date 2024-12

Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration

Ahn, Jun-Yeong,Kim, Somi,Rok Kim, Chang,Ji-Hyun Lee,Kim, Jong Min,Thomas M. Klompstra,Ha Choi, Yoon,Jeon, Yoon,Na, Yongwoo,Jong-Seo Kim,Okada, Yuki,Lee, Ho,Kim, Ik Soo,Kim, Jong Kyoung,Bon-Kyoung Koo,Baek, Sung Hee

Developmental Cell, v.59, no.23, pp.3089 - 3105

Publication Date 2024-11

GTSE1-driven ZEB1 stabilization promotes pulmonary fibrosis through the epithelial-to-mesenchymal transition

Jin, Hee,So-Yeon Park,Lee, Ji Eun,Park, Hangyeol,Jeong, Michaela,Lee, Hyukjin,Cho, Jaeho,Lee, Yun-Sil

Molecular Therapy, v.32, no.11, pp.4138 - 4157

Publication Date 2024-11

Gastric Organoid, a Promising Modeling for Gastric Stem Cell Homeostasis and Therapeutic Application

Lee, Subin,Jang-Hyun Choi,Park, So-Yeon,Jihoon Kim

International Journal of Stem Cells, v.17, pp.337 - 346