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Introduction

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• We focus on developing programmable nucleases that enable genome editing in plants, animals, and cultured cells including human pluripotent stem cells. These nucleases cleave chromosomal DNA in a targeted manner, producing DNA double-strand breaks (DSBs), whose repair via endogenous mechanisms gives rise to targeted genome modification in cells and whole organisms.

Publications

• Xu J.; Beum-Chang Kang; Naing A.H...

  CRISPR/Cas9-mediated editing of 1-aminocyclopropane-1-carboxylate oxidase1 enhances Petunia flower longevity PLANT BIOTECHNOLOGY...

• Yoshimura Y.;Yamanishi A.;Kamitan...

  Generation of targeted homozygosity in the genome of human induced pluripotent stem cells PLOS ONE 14, 12 2019

• Beum‑Chang Kang; Je Wook Woo; S...

  Guidelines for C to T base editing in plants: base-editing window, guide RNA length, and efficient promoter PLANT BIOTECHNOLOGY ...

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