Bioinformatics (BI) is an essential discipline in modern life science. Indeed, BI is so important that most scientific papers published use data that has been obtained through bioinformatics analysis techniques.
At the CGE, nine different teams are working on projects in five categories. These projects involve 1) the development of genome editing tools, 2) the application of genome editing tools to various species, 3) the development of conditional knockout cassettes, 4) research on single cell/spatial genomics based on mosaic genetics, and 5) organoid screening. The BI team conducts joint research, developing and maintaining the code and analytic pipelines, the databases, and the web services derived from these projects. Furthermore, we hold journal clubs and lectures prepared by team members, including the BI team leader, to enhance the bioinformatics knowledge of the members of the CGE. We hold single-cell/spatial genomics workshops, which are open to researchers at the CGE as well as those based at other institutes as we strive to facilitate communication and collaboration between our own staff members and external scientists. The Bioinformatics Facility is led by senior researcher Dr. Heetak Lee, with support from Ph.D. candidate Youngchul Oh and undergraduate student Yeongjoon Kim. Most analysis is performed with high performance PCs, and large-capacity analysis is performed on the Olaf server at the Institute for Basic Science.
The CGE’s Bioinformatics Facility’s work includes the following:
- 1. Consult on what kind of bioinformatic results are needed for a project
- 2. Generate top results and enhance them based on constructive discussions
- 3. Collaborate both with internal and external researchers
- 4. Develop and maintain analytic pipelines, databases, and web services
- 5. Act as a bridge between CGE researchers and external BI collaborators
- 6. Hold lectures and journal clubs to share BI knowledge with all CGE members
Contact: Heetak Lee (leeheetak@ibs.re.kr)
