Measuring the True Nature of 3D Models with W8
Spheroids and organoids represent a major advancement in pharmaceutical and biomedical research due to their ability to better mimic in vivo conditions. However, their complex 3D structure introduces significant variability, limiting reproducibility and hindering standardization. Current approaches to address this heterogeneity largely rely on size-based selection, often using technologies adapted from 2D analysis, which remain insufficient to capture true biophysical properties.
This seminar presents the W8 system as a non-destructive, label-free solution for direct measurement of key parameters such as size, weight, mass density, circularity, and solidity of individual organoids in real time. By moving beyond conventional morphology-based assessment, W8 enables a more accurate and comprehensive understanding of organoid heterogeneity. Applications in drug screening, organoid research, and quality control will be discussed, highlighting how improved biophysical characterization can enhance reproducibility and experimental reliability.
